Dr. McCreary’s primary research interests focus on a “bench to bedside” approach of optimizing pharmacokinetic and pharmacodynamic principles for antimicrobial utilization and translational antibiotic stewardship initiatives. In less than 18 months at UPMC, she led and implemented stewardship initiatives including: dose-optimization of anti-pseudomonal beta-lactam antibiotics, comprehensive antimicrobial dosing chart by indication, transplant prophylaxis guideline updates, novel necrotizing skin and soft tissue infection pathway, evaluation and assessment of beta-lactam allergy pathway, vancomycin area-under-the-curve-based dosing pharmacokinetic service, and antifungal stewardship.
Dr. McCreary is a pharmacist who specializes in the management of patients infected by drug-resistant and/or fungal pathogens. She serves as a preceptor for PGY1 and PGY2 pharmacy residents. She also leads infectious diseases quality improvement initiatives for UPMC system, coordinating with the 35 US-based hospitals to optimize the care of any patient receiving any antimicrobial. She serves as the Chair of the UPMC System COVID-19 Therapeutics Committee.
Dr. McCreary lectures in the School of Medicine, providing education on antimicrobial agents, pharmacokinetics/pharmacodynamics, and the rationale use of antibiotics. She also provides mentorship for medical and pharmacy trainees pursing clinical and translational research.
- BS, Biomedical Sciences, Auburn University College of Science and Mathematics, 2011
- PharmD, Auburn University Harrison School of Pharmacy, 2015
- PGY1 Residency, Pharmacy, University of Wisconsin Health, 2016
- PGY2 Residency, Infectious Diseases Specialty, University of Wisconsin Health, 2017
Education & Training
Dorazio J., Chiappelli A. L., Shields R. K., Tsai Y. V., Skinker P., Nabozny M. J., Bauza G., Forsythe R., Rosengart M. R., Gunn S. R., Marini R., Marini R., Falcione B., Ludwig J., McCreary E. K. Clindamycin plus Vancomycin versus Linezolid for Treatment of Necrotizing Soft Tissue Infection. Open Forum Infectious Diseases. 2023
McCreary E. K., Johnson M. D., Jones T. M., Spires S. S., Davis A. E., Dyer A. P., Dodds-Ashley E., Gallagher J. C. Antibiotic Myths for the Infectious Diseases Clinician. Clinical Infectious Disease. 2023
McCreary E. K., Lemon L., Megli C. Monoclonal Antibodies for Treatment of SARS-CoV-2 Infection During Pregnancy: A Cohort Study. Annals of Internal Medicine. 2022
McCreary E. K., Kip K. E., Collins K. Evaluation of Bebtelovimab for Treatment of COVID-19 During the SARS-CoV-2 Omicron Variant Era. Open Forum Infectious Diseases. 2022
McCreary E. K., Heil E. L., Tamma P. D. New Perspectives on Antimicrobial Agents: Cefiderocol. Antimicrobial Agents Chemotherapy. 2021
McCreary E. K., Bariola J. R., Minnier T. E. The comparative effectiveness of COVID-19 monoclonal antibodies: A learning health system randomized clinical trial. Contemporary Clinical Trials. 2022
McCreary E. K., Angus D. C. Efficacy of Remdesivir in COVID-19. Journal of the American Medical Association. 2020; 324(11): 1041-1042.
McCreary E. K., Byers K., Fernandes C., Kline E., Nicolau D. P., Shields R. K. Shields RK. Plasma and cerebrospinal fluid therapeutic drug monitoring of ceftolozane and tazobactam during treatment of pan-ß-lactam-resistant Pseudomonas aeruginosa meningitis. Open Forum Infectious Disease. 2020; 7(12)
McCreary E. K., Nguyen M. H., Davis M. R., Borlagdan J., Shields R. K., Anderson A. D., Rivosecchi R. M., Marini R. V., Sacha L. M., Silveira F. P., Andes D. R., Lepak A. J. Achievement of clinical isavuconazole blood concentrations in transplant recipients with isavuconazonium sulphate capsules administered via enteral feeding tube. The Journal of Antimicrobial Chemotherapy. 2020; 75(10): 3023-3028.
McCreary E. K., Bayless M., Van A. P., Lepak A. J., Wiebe D. A., Schulz L. T., Andes D. R. Impact of Triazole Therapeutic Drug Monitoring Availability and Timing. . 2019; 63(10)
- Congressional Citizenship Award, 2008
- Society of Infectious Diseases Pharmacists Executive Board Member, 2020-2022
- First Place in Innovation - UPMC Quality and Safety Fair 2020, 2020
- Distinguished Alumnus - Auburn University Rho Chi Chapter, 2021
- UPMC Award for Commitment and Excellence in Service (ACES), 2021
- ACCP Infectious Diseases Practice and Research Network New Practitioner Award, 2022
- IDSA Clinical Practice Innovation Award, 2022
- Auburn University Young Alumni Achievement Award, 2022
