Dr. Zabbarova’s main research interests lie in studying the mechanisms for the development of bladder dysfunction, especially the one caused by aging, spinal cord injury (SCI) and pelvic organ irradiation (radiation cystitis) and examination of potential therapeutic options.
- MSci, Biophysics, Moscow State University, 2001 (Magna cum laude)
- PhD, Medical Biophysics, Moscow State University, 2004
Education & Training
Zabbarova I, Tyagi P, Ikeda Y, Yan X, Ginjupally V, Percy S, Wolf-Johnson A, Tyagi S, Drake M, Andersson K-E, Wein A, Fry C, Kanai A. Endogenous vasopressin and vasopressin receptor 2 in bladder as anti-diuretic / anti-spasmodic targets for the treatment of multifactorial nocturia. Continence (Amst). 2025 Dec;16:102292. PMID: 41503219.
Zabbarova IV, Ikeda Y, Kozlowski MG, Tyagi P, Birder L, Chakrabarty B, Perera S, Dhir R, Straub AC, Sandner P, Andersson KE, Drake M, Fry CH, Kanai A. Benign Prostatic Hyperplasia/Obstruction Ameliorated Using a Soluble Guanylate Cyclase Activator. J Pathol. 2022 Apr:256(4):442-454. PMID: 34936088.
Zabbarova IV, Ikeda Y, Carder EJ, Wipf P, Wolf-Johnston AS, Birder LA, Yoshimura N, Getchell SE, Almansoori K, Tyagi P, Fry CH, Drake MJ, Kanai AJ. Targeting p75 neurotrophin receptors ameliorated spinal cord injury-induced detrusor sphincter dyssynergia in mice. Neurourol Urodyn. 2018 Nov;37(8):2452-2461. PMID:29806700.
Ikeda Y, Zabbarova IV, Birder LA, Wipf P, Getchell SE, Tyagi P, Fry CH, Drake MJ, Kanai AJ. Relaxin-2 therapy reverses radiation-induced fibrosis and restores bladder function in mice. Neurourol Urodyn. 2018 Nov;37(8):2441-2451. PMID:29806709.
Zabbarova I, Kanai A. Targeted Delivery of Radioprotective Agents to Mitochondria. Molec Interventions 2008 Dec; 8(6): 294-302. PMID: 19144902
- Research grant award, Pfizer OAB-LUTS Competitive Grants Program, 2009
- Research grant award, Samuel & Emma Winters Foundation, 2009
- CURE-UAB Travel Scholarship Award, 2015
- Translational Junior Faculty Research Award, 15th Annual Research Day Department of Medicine, University of Pittsburgh, 2017
- Best Non-Clinical Abstract, Annual Meeting of the International Continence Society, Madrid, Spain, 2024
