Jaideep Behari, MD, PhD

  • Professor of Medicine
  • Chief (interim), Gastroenterology, Hepatology and Nutrition
  • Director, UPMC Liver Steatosis and Metabolic Wellness Program
  • Associate Director, Pittsburgh Liver Research Center (PLRC)
Academic Interests

Dr. Behari is a Professor whose research investigates the role of intracellular signaling pathways in the pathogenesis of liver diseases. He is also interested in nonalcoholic fatty liver disease, alcoholic fatty liver disease and hepatocellular carcinoma.

    Education & Training

  • MBBS, University of Rajasthan, 1993
  • PhD, University of Georgia, 1998
  • Internal Medicine Residency, University of Massachusetts, 2002
  • Internal Medicine Residency, University of Pittsburgh, 2003
  • Fellowship, Gastroenterology/Hepatology, University of Pittsburgh, 2006
  • Research Fellowship, Massachusetts General Hospital/ Harvard Medical School, 2000
Recent Publications

Behari, J., Yeh, T.H., Krauland, L., Otruba, W., Cieply, B., Hauth, B., Apte, U., Wu, T., Evans, R., Monga, S.P. Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis. American Journal of Pathology. 2010; 176(2): 744-53.


Yeh, T.H., Krauland, L., Singh, V., Zou, B., Devaraj, P., Stolz, D.B., Franks, J., Monga, S.P., Sasatomi, E., Behari, J. Liver-specific B-Catenin Knockout Mice Have Bile Canalicular Abnormalities, Bile Secretory Defect and Intrahepatic Cholestasis. Hepatology. 2010; 52(4): 1410-9.


Liu, S., Yeh, T.H., Singh, V.P., Shiva, S., Krauland, L., Li, H., Zhang, P., Kharbanda, K., Ritov, V., Monga, S.P., Scott, D.K., Eagon, P.K., Behari, J. B-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice. Hepatology. 2012; 55(3): 931-40.


Ganesh, S., Rogal, S.S., Yadav, D., Humar, A., Behari, J. Risk Factors for Frequent Readmissions and Barriers to Transplantation in Patients with Cirrhosis. PLoS One. 2013; 8(1): e55140.


Rachakonda, V., Gabbert, C., Raina, A., Li, H., Malik, S., DeLany, J.P., Behari, J. Stratification of Risk of Death in Severe Acute Alcoholic Hepatitis Using a Panel of Adipokines and Cytokines. Alcoholism: Clinical and Experimental Research. 2014; 38(11): 2712-21.
Dudekula, A., Rachakonda, V., Shaik, B., Behari, J. Weight Loss in Nonalcoholic Fatty Liver Disease Patients in an Ambulatory Care Setting is Largely Unsuccessful but Correlates with Frequency of Clinic Visits. PLoS One. 2014; 9(11): e111808.


Behari, J., Li, H., Liu, S., Stefanovic-Racic, M., Alonso, L., O'Donnell, C.P., Shiva, S., Singamsetty, S., Watanabe, Y., Singh, V.P., Liu, Q. B-Catenin Links Hepatic Metabolic Zonation with Lipid Metabolism and Diet-induced Obesity in Mice. American Journal of Pathology. 2014; 184(12): 3284-98.


Rachakonda, V., Gabbert, C., Rain, A., Bell, L.N., Cooper, S., Malik, S., Behari, J. Serum metabolomic profiling in acute alcoholic hepatitis identifies multiple dysregulated pathways. PLoS One. 2014; 9(12): e113860.
Behari, J., Sylvester, K.G. Role of the Wnt/B-catenin pathway in the pathogenesis of alcoholic liver disease. Current Molecular Pharmacology. 2015


Rachakonda, V., Borhani, A.A., Dunn, M.A., Andrzejewski, M., Martin, K., Behari, J. Serum leptin is a biomarker of malnutrition in decompensated cirrhosis. PLoS One. 2016

    Honors and Awards
  • Ruth L. Kirschstein National Research Service Award, 2004-2006
  • Poster of Distinction, 56th Annual Meeting of AASLD, 2005
  • UPMC Award for Commitment and Excellence in Service (ACES), 2024