Joo Heung Yoon, MD

  • Assistant Professor of Medicine
  • Faculty, Center for AI Innovation in Medical Imaging
  • Faculty, Pittsburgh Space Initiative
Academic Interests

I have been interested in identifying hidden patterns of pathologic state with machine learning, and developing prediction models with using a large-scale clinical data. With the collaborations with the School of Machine Learning, Carnegie Mellon University, I have been building various prediction models using supervised ML as well as deep neural network. My exploration on the multigranular, multimodal clinical data allowed our research team to identify risks for impending shock and hypovolemia, and prompted to generate reinforcement learning-driven simulation of shock management. My current scope of work expands to the development of physiologic foundation model and leveraging few state-of-the-art large language models for unconventional clinical data utilization.

As a critical care physician, I spend most of my time in the Intensive Care Unit (ICU). My clinical interests are shock and resuscitation, especially on identifying etiologies of physiologic deterioration from various acute illnesses.

In the ICU, I provide structural teaching to house staffs and medical students at a daily basis. I like to teach cardiopulmonary physiology and resuscitation, that includes pulmonary mechanics, use of vasopressors/inotropes, response to resuscitation, and post-cardiac arrest care. Also I teach clinical informatics to medical students and bedside rounding teams as needed.

    Education & Training

  • MD, Catholic University of Korea, Seoul, South Korea, 2002
  • Internship, Internal Medicine, Maimonides Medical Center - SUNY Downstate, 2007
  • Residency, Internal Medicine, New York Medical College, 2009
  • Research Fellowship, Massachusetts General Hospital / Harvard Medical School, 2011
  • Research Fellowship, Beth Israel Deaconess Medical Center / Harvard Medical School, 2014
  • Fellowship, Pulmonary and Critical Care Medicine, University of Pittsburgh School of Medicine, 2017
Recent Publications

Yoon JH, Kim J, Lagattuta T, Hravnak M, Pinsky MR, Clermont G. Early Physiologic Numerical and Waveform Characteristics of Hemorrhage During the Blood Donation. Critical Care Explorations. 2024; 6(4): e1073.

Kang S, Yoon JH. Current Challenges in Adopting Machine Learning to Critical Care and Emergency Medicine. Clinical and Experimental Emergency Medicine. 2023; 10(2): 132-137.

Yoon JH, Pinsky MR, Clermont G. Artificial Intelligence in Critical Care Medicine. Critical Care. 2022; 26(75): 1-9.
Chen Y, Yoon JH, Pinsky MR, Clermont G. Development of hemorrhage identification model using non-invasive vital signs. Physiol Meas. 2020; 41(5): 055010.

Yoon JH, Mu L, Chen L, Dubrawski A, Hravnak M, Pinsky MR, Clermont G. Predicting tachycardia as a surrogate for instability in the intensive care unit. J Clin Monit Comput. 2019; doi: 10.1007/s10877-019-00277-0

Yoon JH, Pinsky MR. Predicting adverse hemodynamic events in critically-ill patients. Curr Opin Crit Care. 2018; June;24(3): 196-203.

    Honors and Awards
  • Richard D. Levere Excellence in Teaching Award, New York Medical College, 2008
  • Partners in Excellence Award, 2009
  • Excellence in Clinical Service Award, North Shore Medical Center, 2010
  • Abstract Award, American Thoracic Society, 2018
  • SCCM Gold Snapshot Award, Society of Critical Care Medicine, 2019
  • NIH (NIGMS) K23 - K23GM138984, 2020
  • KARAT (K Awardee to R Advancement Training) Catalyst Award, 2023
  • Abstract Award, American Thoracic Society, 2025
  • NIH (NIGMS) R35 - R35GM159939, 2025
Research Grants

Title: Designing a Comprehensive Machine Learning-driven Prescriptive Clinical Decision Support System for Shock and Associated Critical Care Conditions
Role: Principal Investigator
Funding Agency: National Institute of Health
Grant Number: R35 GM159939
Start Year: 2025
End Year: 2030