Kenneth E. Fasanella, MD

  • Associate Professor of Medicine
  • Program Director, Gastroenterology and Hepatology Fellowship
Academic Interests

Dr. Fasanella's research focuses on surveillance of pancreatic cystic lesions, biomarkers of risk in Barrett's esophagus, and outcomes of endoscopic treatment of high risk Barrett's esophagus and Barrett's related neoplasia.

Dr. Fasanella specializes in the diagnosis and treatment of upper gastrointestinal disorders, including GERD, dysphagia, Barrett's esophagus and associated early esophageal cancer. He is very experienced in the use of endoscopic ultrasound in diagnosis and staging of malignancies, including esophageal, gastric, pancreatic, and rectal cancers, and the evaluation and surveillance of pancreatic cystic lesions and submucosal lesions of the GI tract. He is experienced in the use of deep (balloon-assisted) enteroscopy for the evaluation and treatment of obscure GI bleeding. Additionally, he has extensive experience in the clinical treatment of the gastrointestinal manifestations of systemic sclerosis.

Dr. Fasanella has served as the Program Director of the Gastrointestinal Fellowship Program at UPMC since 2012, and prior to that, as the Associate Program Director, since 2007. He is interested in assessment tools for endoscopic competence.

    Education & Training

  • BA, University of Virginia, 1996
  • MD, University of Virginia School of Medicine, 2001
  • Residency, Internal Medicine, Duke University Medical Center, 2004
  • Fellowship, Gastroenterology, University of Pittsburgh Medical Center, 2007
  • Advanced Fellowship, Endoscopic Ultrasound and non-biliary therapeutic endoscopy, University of Pittsburgh Medical Center, 2008
Recent Publications

Fasanella, K.E., McGrath, K.M., Sanders, M., Brody, D., Domsic, R., Khalid, A. Pancreatic endocrine tumor EUS-guided FNA DNA microsatellite loss and mortality. Gastrointestinal Endoscopy. 2009; 69(6): 1074-80.

Fasanella, K.E., Krasinskas, A., Schoedel, K.E., Sasatomi, E., Slivka, A., Whitcomb, D.C., Sanders, M., Nodit, L., Raab, S., McGrath, K.M., Ohori, N.P., Khalid, A. DNA mutational differences in cytological specimens from pancreatic cancer and cholangiocarcinoma. Pancreatology. 2010; 10(4): 429-33.

Rockacy, M.J., Zahid, M., McGrath, K.M., Fasanella, K.E., Khalid, A. Association between KRAS mutation, detected in pancreatic cyst fluid, and long-term outcomes of patients. Clinical Gastroenterology and Hepatology. 2013; 11(4): 425-9.

Aggarwal, N., Kuan, S.F., Fasanella, K.E. Endoscopic, ultrasonographic, and pathologic correlation of lymphocytic gastritis. Endoscopy. 2013; 45.

Fasanella, K.E., Bista, R.K., Staton, K., Rizvi, S., Uttam, S., Zhao, C., Sepulveda, A., Brand, R.E., McGrath, K., Liu, Y. Nuclear Nano-architecture Markers of Gastric Cardia and Upper Squamous Esophagus Detect Esophageal Cancer "Field Effect". The Journal of Cancer. 2013; 4(8): 626-34.

Singhi, A.D., Zeh, H.J., Brand, R.E., Nikiforova, M.N., Chennat, J.S., Fasanella, K.E., Khalid, A., Papachristou, G.I., Slivka, A., Hogg, M., Lee, K.K., Tsung, A., Zureikat, A.H., McGrath, K. American Gastroenterological Association guidelines are inaccurate in detecting pancreatic cysts with advances neoplasia: a clinicopathologic study of 225 patients with supporting molecular data. Gastrointestinal Endoscopy. 2016; 83(6): 1107-1117.

    Honors and Awards
  • Member, American Society of Gastrointestinal Endoscopy, 2005 - Present
  • Member, American Gastroenterology Association, 2005 - Present
  • Clinical Fellowship Curriculum Committee, 2007 - Present