Matthew Francis Muldoon, MD, MPH

Dr. Muldoon conducts clinical research examining the interface of behavioral and biological risk factors for cardiovascular disease. Cardiovascular risk conveyed by hypertension, lipid disorders, insulin resistance and pre-clinical atherosclerosis are studied in relation to individual differences health behaviors (diet and exercise), cognition (attention, working memory, executive function, and impulsivity) and in mood (depression and anxiety). In addition, Dr. Muldoon has tested Interventions to treat or prevent hypertension, including prescribed pharmacotherapies, and nutritional supplements. His most recent work leverages e-health technologies to aid patients in self-management of their hypertension. He has lead or co-lead investigations using randomized and double-blind trial design, physiologic and ambulatory recordings, automated and bidirectional short-messaging systems, biomarker assessment, genomics and functional brain imaging. The majority of Dr. Muldoon’s research funding has come from competitive grants awarded by the National Institutes of Health (US Public Health Service).

Dr. Muldoon is a board-certified internist who has long directed the Hypertension Center at the University of Pittsburgh School of Medicine, while also serving as a primary care provider (PCP) at the Pittsburgh VA Healthcare System. He is the founding director of the Heart and Vascular Institute’s Hypertension Center which serves as a regional referral center for severe, secondary and otherwise problematic blood pressure disorders. Here, patients benefit from concurrent assessment and treatment by a certified clinical dietitian and clinical pharmacists as we work collaboratively with patients to optimize BP control through efficient use of both behavioral and pharmacology therapies. We seek discovery of individualized treatment for each patient based upon their medical history and current circumstances, both medical and psychosocial. At the Pittsburgh VA, Dr. Muldoon serves as a senior and widely-experienced primary care provider for a panel of our country’s veterans while also training internal medicine interns and residents in thorough, compassionate and cost-effective general outpatient care.