Obaid S. Shaikh, MD, FRCP

  • Professor of Medicine
  • Director, Transplantation Medicine, VA Pittsburgh Healthcare System
Academic Interests

Dr. Shaikh is a Professor of Medicine whose research efforts focus on progression of endstage liver disease, treatment of hepatocellular carcinoma, hepatocarcinogenesis and genomic profiling of liver tumors, and allocation models for liver transplantation.

    Education & Training

  • MBBS, Dow Medical College, Karachi, Pakistan, 1979
  • MRCP, Royal College of Physicians, London (UK), 1985
  • Registrar, Medicine/Gastroenterology, Whiston Hospital - Prescot, UK, 1991
  • Fellowship, Gastroenterology/Hepatology, University of Southern California - Los Angeles, 1993
  • Clinical Associate, Hepatology, NIH - Bethesda, 1995
  • Fellowship, Transplantation Medicine, University of Pittsburgh, 1996
Recent Publications

Ragni, M.V., Moore, C.G., Soadwa, K., Nalesnik, M.A., Zajko, A.B., Cortese-Hassett, A., Whiteside, T.L., Hart, S., Zeevi, A., Li, J., Shaikh, O.S. Impact of HIV on liver fibrosis in men with hepatitis C infection and haemophilia. Haemophilia. 2011; 17(1): 103-11.

Taylor, R.M., Tujios, S., Jinjuvadia, K., Davern, T., Shaikh, O.S., Han, S., Chung, R.T., Lee, W.M., Fontana, R.J. Short and long-term outcomes in patients with acute liver failure due to ischemic hepatitis. Digestive Diseases and Sciences. 2012; 57(3): 777-85.

Terrault, N., Reddy, R., Poordad, F., Curry, M., Schiano, T., Shaikh, O., Dove, L., Shetty, K., Millis, M., Schiff, E., Regenstein, F., Barnes, D., Barin, B., Peters, M., Roland, M. Peginterferon and Ribavirin for Treatment of Recurrent Hepatitis C Disease in HCV-HIV Coinfected Liver Transplant Recipents. The American Journal of Transplantation. 2014; 14(5): 1129-35.

Rogal, S.S., Hu, A., Bandi, R., Shaikh, O. Novel therapy for non-cirrhotic hyperammonemia due to a spontaneous splenorenal shunt. World Journal of Gastroenterology. 2014; 20(25): 8288-91.

Butt, A.A., Yan, P., Bonilla, H., Abou-Samra, A.B., Shaikh, O.S., Simon, T.G., Chung, R.T., Rogal, S.S. Effect of addition of statins to antiviral therapy in hepatitis C virus-infected persons: Results from ERCHIVES. Hepatology. 2015; 62(2): 365-74.

Butt, A.A., Yan, P., Shaikh, O.S., Freiberg, M.S., Lo Re, V. 3rd, Justice, A.C., Sherman, K.E. Virologic response and haematologic toxicity of boceprevir- and telaprevir-containing regimens in actual clinical settings. The Journal of Viral Hepatitis. 2015; 22(9): 691-700.

Butt, A.A., Yan, P., Shaikh, O.S., Chung, R.T., Sherman, K.E. Sofosbuvir-based Regimens in Clinical Practice Achieve SVR Rates Closer to Clinical Trials. Liver International. 2015

Lau DTY, Ganov-Raeva L, Wang J, Mogul D, Chung RT, Lisker-Melman M, Chang KM, Shaikh OS, Janssen HLS, Wahed AS, Lok AS. Precore and Basal Core Promoter Hepatitis B (HBV) Variants are Present from a Young Age and Differ Across HBV Genotypes. Hepatology. 2020; Aug

Shaikh OS, Rogal S, Malik A, Sharma V, Cacciarelli T. Liver Transplant from Increased-risk Donors in the Era of Direct-acting Antivirals for Hepatitis C. Experimental Clinical Transplantation. 2019; July

    Honors and Awards
  • Royal College of Physicians, London, FRCP, 2003
  • Transplant Workshop. Hot topics in organ allocation: roadway to a fairer system. AASLD annual meeting, Boston. Course co-director., 2009