Ravy K. Vajravelu, MD, MSCE

  • Assistant Professor of Medicine
  • Associate Program Director—Research Pathway: UPMC Gastroenterology Fellowship
  • Staff Gastroenterologist: VA Pittsburgh Healthcare System
  • Affiliate Investigator: CHERP, VA Pittsburgh Healthcare System
Academic Interests

Dr. Vajravelu's long-term research goal is to develop precision medicine tools that inform therapeutic decision making in gastroenterology by integrating insights from across biomedical science. He is pursuing this goal through three complementary objectives:

(1) To design biostatistical methods to efficiently analyze high-dimensional clinical datasets
(2) To build epidemiologic models of gastroenterology conditions such as colorectal cancer, Barrett’s esophagus, and gastroesophageal reflux
(3) To develop informatics approaches to integrate diverse biomedical data for clinical prediction.

These research objectives are funded by grants from the National Institutes of Health (https://reporter.nih.gov/search/UgkJORp_90y2gPXCt1PjnQ/projects). By completing these objectives, Dr. Vajravelu and his multidisciplinary research team aim to develop algorithms to provide gastroenterology patients and providers with precision screening and therapeutics recommendations.

Dr. Vajravelu is a gastroenterologist at VA Pittsburgh Healthcare System. He diagnoses and treats general gastroenterology conditions such as gastroesophageal reflux, abdominal pain, diarrhea, constipation, and gastrointestinal bleeding. He performs colorectal cancer screening by colonoscopy.

As a teaching attending at VA Pittsburgh Healthcare System, Dr. Vajravelu trains of gastroenterology fellows in inpatient gastroenterology consultation, outpatient gastroenterology practice, and gastrointestinal endoscopy. He particularly enjoys teaching medical trainees about consensus guidelines, especially in relation to knowledge gaps in the literature that may adversely affect patient care. He also teaches prediction modeling and machine learning to epidemiology graduate students. He hopes to help trainees identify the topics and techniques they will pursue in their careers to advance patient care.

    Education & Training

  • BS, Biomedical Engineering, Johns Hopkins University, 2008
  • MD, Case Western Reserve University, 2012
  • MSCE, University of Pennsylvania, 2018
  • Residency, Internal Medicine, Hospital of the University of Pennsylvania, 2015
  • Fellowship, Gastroenterology, Hospital of the University of Pennsylvania, 2018
    Honors and Awards
  • Tau Beta Pi Engineering Honor Society, 2008
  • Edward C. Raffensperger Teaching Award for Gastroenterology Fellows, University of Pennsylvania, 2018
  • Sidney Cohen Teaching Award for Gastroenterology Faculty, University of Pennsylvania, 2020
  • Associate Editor, Pharmacoepidemiology and Drug Safety, 2020-2024
Research Grants

R01 DK135876, Determining medications associated with drug-induced pancreatic injury through novel pharmacoepidemiology techniques that assess causation, PI, 2023-2027.