Dr. Nouraie's outstanding skills as a biostatistician and epidemiologist helped facilitate the development of several key studies in the area of sickle cell disease and chronic cardiopulmonary disorders, including projects on environmental exposure and pulmonary diseases, natural history and predictors of pulmonary hypertension in sickle cell disease, and application of big administrative data in epidemiology of cardiopulmonary diseases. His research on the design and analysis of clinical studies in the area of GI benign and malignant disease, sickle cell, and cardiopulmonary disorders has resulted in over 350 peer-reviewed publications. Currently, he is interested in assessing risk stratification models and biomarker validation in cardiopulmonary diseases and longevity.
Dr. Nouraie has been involved in teaching applied statistical methods, clinical epidemiology, and study design. His education interests also include the application of biostatistical methods in causal inference and biomarker validation.
- MD, Tehran University of Medical Sciences, 1996
- PhD, Epidemiology, Tehran University of Medical Sciences, 2000
Education & Training
Wood KC, Nouraie SM, Gladwin MT, Novelli EM, Gordeuk VR, Morris CR, Minniti CP, Ataga KI, Desai PC, Abebe KZ, Straub AC. The CYB5R3 T117S Missense Variant is Associated with Attenuated Riociguat Efficacy in Sickle Cell Disease. Blood. 2026 Jul 8:blood.2026034193. PMID: 42418684.
Yang A, Seedahmed MI, Rosser FJ, Wojcik R, Sharma L, Bain W, Bon J, Chandra D, Dela Cruz CS, Königshoff M, Morris A, Wenzel SE, Goobie GC, Nouraie SM. How the Exposome Shapes Our Respiratory Health. Am J Respir Crit Care Med. 2026 Jul 1:aamag338. PMID: 42384921.
Chan ZM, Patel PP, Levitsky GM, McClung CA, Nouraie SM, Kelly NJ. Heart rate phase is an indicator of chronotype-relevant circadian shifts associated with human disease: an All of Us Research Program analysis. J Physiol. 2026 Apr;604(8):3282-3296. PMID: 41839809.
Baker S, Nouraie SM, Steinman RA. Residency matches of MD-PhD versus MD-only students: compatibility with continued research momentum. JCI Insight. 2026 Jun 22;11(12):e202606. PMID: 42325090.
Xue S, Nouraie SM, Wang J, Li X, Meyers D, Bleecker ER, Ortega VE, Castro M, Denlinger LC, Erzurum S, Israel E, Woodruff P, Moore WC, Christenson S, Fahy J, Sumino K, Jarjour N, Levy B, Wenzel SE. A cross-sectional study of oxidative stress pathway genotypes and their interactions with environmental pollutant levels identifies associations with gene expression and lung function. EBioMedicine. 2026 Jul;129:106334. PMID: 42336761.
Xue S, Broerman MJ, Goobie GC, Kass DJ, Fabisiak JP, Wenzel SE, Nouraie SM. Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches. Environ Sci Technol. 2025 Apr 1;59(12):5936-5945. PMID: 40119855.
Naiditch H, Talisa VB, Magnani JW, Nouraie SM, Yende S, Mayr FB. Identifying racial inequalities in long-term outcomes among survivors of critical illness with sepsis in a US cohort: a retrospective cohort study. BMJ Open. 2025 Nov 24;15(11):e102801. PMID: 41290296.
Goobie GC, Marinescu DC, Adegunsoye A, Bourbeau J, Carlsten C, Clifford RL, Doiron D, Duan Q, Gibson KF, Grant-Orser A, Hernandez Cordero AI, Johannson KA, Kass DJ, Kim SE, Leung JM, Li X, Tan W, Yang CX, Nouraie SM, Ryerson CJ, Hackett TL, Zhang Y. Accelerated epigenetic ageing worsens survival and mediates environmental stressors in fibrotic interstitial lung disease. Eur Respir J. 2025 Jun 5;65(6):2401618. PMID: 39884761.
Goobie GC, Assadinia N, Yang CX, Chu F, Clifford RL, Cooper JD, Fabisiak JP, Gibson KF, Johannson KA, Kass DJ, Kim SE, Li X, Lindell KO, Marinescu DC, Vasilescu DM, Wang V, Carlsten C, Nouraie SM, Ryerson CJ, Hackett TL, Zhang Y. Epigenome-Wide Analysis Identifies Pollution-Sensitive Loci in Fibrotic Interstitial Lung Disease. Am J Respir Crit Care Med. 2025 Oct;211(10):1835-1845. PMID: 40540633.
Babu V, Little JA, Morris CR, Machado R, Gibbs S, Kato GJ, Gordeuk VR, Gladwin MT, Zhang Y, Nouraie SM. Targeted Proteomic Analysis of Sickle Cell Disease Patients With Elevated Tricuspid Regurgitation Velocity. Proteomics Clin Appl. 2025 Sep;19(5):e70019. PMID: 40785364.
