A Professor Emerita of Medicine, Dr Greenspan is dually-trained in Geriatrics and in Endocrinology, and she serves as UPMC’s Director of the Osteoporosis Prevention and Treatment Center and as Director of Bone Health at Magee Women’s Hospital. Her research focuses on geriatric osteoporosis, including its pathophysiology, evaluation, and treatment. Her current R01s focus on osteoporosis in institutionalized elderly, including new treatment modalities and new assessments of bone strength. In addition, she is PI of our NIH-funded “Pepper Center” and also our NIH T32 Program entitled “Pitt Integrated Clinical and Geroscience Research Training Program”. A former member of NIH/NIA’s Board of Scientific Counselors, NIA’s Clinical Trial Advisory Panel, she now serves on NIA’s National Advisory Council on Aging. She is also Past President of the Bone Health Osteoporosis Foundation (previously known as the National Osteoporosis Foundation).
- BA, Stanford University, 1975
- MD, Harvard Medical School, 1979
- Residency, Internal Medicine, Beth Israel Deaconess Medical Center, 1982
- Postdoctoral Fellow, Endocrinology, Massachusetts General Hospital, 1985
- Postdoctoral Fellow, Geriatrics, Beth Israel Deaconess Medical Center, 1986
Education & Training
Kotlarczyk MP, Perera S, Ferchak MA, Nace DA, Resnick NM, Greenspan SL. Vitamin D deficiency is associated with functional decline and falls in frail elderly women despite supplementation. Osteoporos Int. 2017 Apr;28(4):1347-1353. PMID: 27975302.
Greenspan SL, Perera S, Ferchak MA, Nace DA, Resnick NM. Efficacy and safety of single-dose zoledronic acid for osteoporosis in frail elderly women: a randomized clinical trial. JAMA Intern Med. 2015 Jun;175(6):913-21. PMID: 25867538
Greenspan SL, Bone HG, Ettinger MP, Hanley DA, Lindsay R, Zanchetta JR, Blosch CM, Mathisen AL, Morris SA, Marriott TB; Treatment of Osteoporosis with Parathyroid Hormone Study Group. Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial. Ann Intern Med. 2007 Mar 6;146(5):326-39. PMID: 17339618.
Greenspan SL, Schneider DL, McClung MR, Miller PD, Schnitzer TJ, Bonin R, Smith ME, DeLucca P, Gormley GJ, Melton ME. Alendronate improves bone mineral density in elderly women with osteoporosis residing in long-term care facilities. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2002 May 21;136(10):742-6. PMID: 12020142.
Greenspan SL, Resnick NM, Parker RA. Combination therapy with hormone replacement and alendronate for prevention of bone loss in elderly women: a randomized controlled trial. JAMA. 2003 May 21;289(19):2525-33. PMID: 12759324.
Greenspan SL, von Stetten E, Emond SK, Jones L, Parker RA. Instant vertebral assessment: a noninvasive dual X-ray absorptiometry technique to avoid misclassification and clinical mismanagement of osteoporosis. J Clin Densitom. 2001 Winter;4(4):373-80. PMID: 11748342.
Greenspan SL, Myers ER, Kiel DP, Parker RA, Hayes WC, Resnick NM. Fall direction, bone mineral density, and function: risk factors for hip fracture in frail nursing home elderly. Am J Med. 1998 Jun;104(6):539-45. PMID: 9674716.
Greenspan SL, Maitland LA, Myers ER, Krasnow MB, Kido TH. Femoral bone loss progresses with age: a longitudinal study in women over age 65. J Bone Miner Res. 1994 Dec;9(12):1959-65. PMID: 7872062.
Greenspan SL, Myers ER, Maitland LA, Resnick NM, Hayes WC. Fall severity and bone mineral density as risk factors for hip fracture in ambulatory elderly. JAMA. 1994 Jan 12;271(2):128-33. PMID: 8264067.
Resnick NM, Greenspan SL. 'Senile' osteoporosis reconsidered. JAMA. 1989 Feb 17;261(7):1025-9. PMID: 2644455.
- Editorial Board, Journal of Gerontology: Medical Sciences, 1999-present
- Editorial Board, Journal of Clinical Densitometry, 1998-present
- Editorial Board, National Osteoporosis Foundation, 2004-present
- Board of Trustees, National Osteoporosis Foundation, 2010-present
- NIH/NIA Board of Scientific Counselors (BSC), 2011-present
- Chair, Education Committee, National Osteoporosis Foundation, 2013-present
- NIH/NIA Clinical Trials Advisory Program (CTAP), 2014-present
- Vice President, National Osteoporosis Foundation, 2016-2018
- President, National Osteoporosis Foundation, 2018-2020
- Past President, National Osteoporosis Foundation/Bone Health Osteoporosis Foundation, 2020-2021
