Dr. Suber studies host defense mechanisms in intrapulmonary bacterial infections that lead to acute respiratory distress syndrome. She has also studied how regulation of protein stability by the ubiquitin-proteasome pathway modulates lung epithelial responses during inflammation.
Dr. Suber's clinical interests include acute respiratory distress syndrome, sepsis, and bacterial pulmonary infections including Klebsiella pneumoniae and Streptococcal pneumoniae.
Dr. Suber is actively involved in the recruitment and retention of talented internal medicine trainees to the University of Pittsburgh. She also teaches medical students and residents in the medical intensive care unit.
- BS ,Chemistry, University of North Carolina at Chapel Hill, 2002
- MD, Johns Hopkins University School of Medicine, 2010
- PhD, Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 2010
- Residency, Internal Medicine, Johns Hopkins Hospital, 2013
- Fellowship, Pulmonary and Critical Care Medicine, University of Pittsburgh School of Medicine, 2018
Education & Training
Suber TL, Nikolli I, O'Brien ME, Londino J, Zhao J, Chen K, Mallampalli RK, Zhao Y. FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. Respir Res. 2018; Oct 25;19(1): 206.
Suber T, Wei J, Jacko AM, Nikolli I, Zhao Y, Zhao J, Mallampalli RK. SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3ß in lung epithelia. The Journal of Biological Chemistry. 2017; 292(18): 7452-7461.
Suber T, Mallampalli RK. An Emerging Role for Megalin as a Regulator of Protein Leak in Acute Lung Injury. Am J Respir Cell Mol Biol. 2017; Nov;57(5): 504-505.
Cai J, Wei J, Li S, Suber T, Zhao J. AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin. Mediators Inflamm. 2017; 2017:6893560: Epub2017Feb27.PubMedPMID:28348461.
- Burroughs Wellcome Fund Postdoctoral Enrichment Program, 2017
- Robert M. Rogers Outstanding Scholarly Achievement Award, University of Pittsburgh, Division of Pulmonary, Allergy, and Critical Care Medicine, 2017
- Ruth L. Kirschstein Postdoctoral Individual National Research Service Award, 2017
